Literature summary for 4.6.1.1 extracted from

Stierl, M.; Stumpf, P.; Udwari, D.; Gueta, R.; Hagedorn, R.; Losi, A.; Gaertner, W.; Petereit, L.; Efetova, M.; Schwarzel, M.; Oertner, T.G.; Nagel, G.; Hegemann, P.
Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa (2011), J. Biol. Chem., 286, 1181-1188.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli strains BL21 (DE3) and BTH101, in Xenopus laevis oocytes, rat hippocampal pyramidal cells, and in the Drosophila melanogaster central nervous system	Beggiatoa sp.

Organism

Organism	UniProt	Comment	Textmining
Beggiatoa sp.	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Co2+-NTA column chromatography	Beggiatoa sp.

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP	-	Beggiatoa sp.	3',5'-cyclic-AMP + diphosphate	-	?

Synonyms

Synonyms	Comment	Organism
bacterial photoactivated adenylyl cyclase	-	Beggiatoa sp.
bPAC	-	Beggiatoa sp.

Cofactor

Cofactor	Comment	Organism	Structure
Calmodulin	-	Beggiatoa sp.

Expression

Organism	Comment	Expression
Beggiatoa sp.	photoactivated adenylyl cyclase activity is increased 300fold in the light	up

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Release 2023.1 (January 2023)