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Literature summary for 4.6.1.1 extracted from

  • Piggott, L.A.; Bauman, A.L.; Scott, J.D.; Dessauer, C.W.
    The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain (2008), Proc. Natl. Acad. Sci. USA, 105, 13835-13840.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
Yotiao the A-kinase anchoring protein Yotiao or AKAP9 binds and regulates adenylyl cyclase in brain, it inhibits AC2 and AC3, but has no effect on AC1 or AC9, the N-terminus of isozyme AC2, AC2-NT, acts as a competitive inhibitor of Yotiao-AC2 interactions, recombinantly expressed Yotiao from HEK293 cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Sprague-Dawley rats
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Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
heart
-
 Rattus norvegicus
-