Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of transgenic mice with disrupted AC5 or overexpressing AC5, the latter type shows less decreased heart rate in later phases within one parabola, the inverse heart rate is more variable in AC5 knockout mice and less variable in AC5 overexpressing mice compared to wild-type mice, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | Mus musculus | the cardiac-specific isozyme AC5 plays an important role in regualting heart rate during parabolic flights, overview | 3',5'-cyclic-AMP + diphosphate | - |
? | |
ATP | Mus musculus C57BL/6 | the cardiac-specific isozyme AC5 plays an important role in regualting heart rate during parabolic flights, overview | 3',5'-cyclic-AMP + diphosphate | - |
? | |
additional information | Mus musculus | type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flight, overview | ? | - |
? | |
additional information | Mus musculus C57BL/6 | type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flight, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P84309 | C57BL/6 mice | - |
Mus musculus C57BL/6 | P84309 | C57BL/6 mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | cardiac isozyme AC5 | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | - |
Mus musculus | 3',5'-cyclic-AMP + diphosphate | - |
? | |
ATP | the cardiac-specific isozyme AC5 plays an important role in regualting heart rate during parabolic flights, overview | Mus musculus | 3',5'-cyclic-AMP + diphosphate | - |
? | |
ATP | - |
Mus musculus C57BL/6 | 3',5'-cyclic-AMP + diphosphate | - |
? | |
ATP | the cardiac-specific isozyme AC5 plays an important role in regualting heart rate during parabolic flights, overview | Mus musculus C57BL/6 | 3',5'-cyclic-AMP + diphosphate | - |
? | |
additional information | type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flight, overview | Mus musculus | ? | - |
? | |
additional information | type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flight, overview | Mus musculus C57BL/6 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AC5 | - |
Mus musculus |
type 5 adenylyl cyclase | - |
Mus musculus |