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Literature summary for 4.6.1.1 extracted from

  • Ueno, K.; Kidokoro, Y.
    Adenylyl cyclase encoded by AC78C participates in sugar perception in Drosophila melanogaster (2008), Eur. J. Neurosci., 28, 1956-1966.
    View publication on PubMed
Search for more literature for 4.6.1.1

Protein Variants

Protein Variants Comment Organism
additional information RNAi against gene AC78C, but not against gene ACXE, depressed the sucrose response in gustatory receptor neurons Drosophila melanogaster

Inhibitors

Inhibitors Comment Organism Structure
MDL-12330A the adenylate cyclase inhibitor depresses the response in GRNs to trehalose as well as sucrose in gustatory receptor neurons Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP Drosophila melanogaster the enzyme, via cAMP, participates in the sugar-taste signaling pathway at the low concentration range, the long form of AC78C product is essential for the normal sugar response in adult flies, overview 3',5'-cyclic-AMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
 gene AC78C
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Source Tissue

Source Tissue Comment Organism Textmining
neuron gustatory receptor neurons Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
 Drosophila melanogaster 3',5'-cyclic-AMP + diphosphate
-
 ?
ATP the enzyme, via cAMP, participates in the sugar-taste signaling pathway at the low concentration range, the long form of AC78C product is essential for the normal sugar response in adult flies, overview Drosophila melanogaster 3',5'-cyclic-AMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
adenylyl cyclase
-
 Drosophila melanogaster