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Literature summary for 4.6.1.1 extracted from
- Modulation of adenyl cyclase activity in the gills of Tapes philippinarum (2004), J. Exp. Zool. A, 301, 952-960.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| forskolin | scarcely stimulated enzyme activity | Ruditapes philippinarum |  |
| GTPgammaS | up to 14fold stimulation | Ruditapes philippinarum | |
| guanosine 5'-(beta,gamma-imido)tri-phosphate | up to 4fold stimulation | Ruditapes philippinarum | |
| serotonin | significant stimulation of enzyme activity | Ruditapes philippinarum | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| HgCl2 | inhibitory at 100microM | Ruditapes philippinarum | |
| Tributyltin chloride | - |
Ruditapes philippinarum | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.77 | - |
ATP | 5mM Mg2+ | Ruditapes philippinarum | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Ruditapes philippinarum | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Ruditapes philippinarum | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ruditapes philippinarum | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| gill | - |
Ruditapes philippinarum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP | - |
Ruditapes philippinarum | 3',5'-cAMP + diphosphate | - |
? | |
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