Application | Comment | Organism |
---|---|---|
drug development | Pure allicin is prepared by reacting synthetic alliin with a stabilized process of the garlic enzyme alliinase. A novel drug vector, polybutylcyanoacrylate (PBCA) nanoparticles has been developed by emulsion polymerization method and wrapps the pure allicin into it. Minimal inhibitory fungal concentration (MIC) and minimal fungicidal concentration (MFC) of pure allicin and PBCA-allicin NPs against six fungus strains (Candida albicans, Cryputococcus neoformans, Trichophyton rubum, Microsporum gypseum, Microsporum canis and Epidermophyton floccosum) in vitro are used to evaluate their anti-fungal efficacy | Allium sativum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Allium sativum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alliin | - |
Allium sativum | allylsulfenic acid + pyruvate + NH3 | pure allicin has significantly stronger in vitro inhibitory effect on the growth of six tested fungi (Candida albicans, Cryputococcus neoformans, Trichophyton rubum, Microsporum gypseum, Microsporum canis and Epidermophyton floccosum) than alliin and alliinase | ? |
Synonyms | Comment | Organism |
---|---|---|
alliinase | - |
Allium sativum |