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Literature summary for 4.2.99.18 extracted from

  • OHara, A.M.; Bhattacharyya, A.; Mifflin, R.C.; Smith, M.F.; Ryan, K.A.; Scott, K.G.; Naganuma, M.; Casola, A.; Izumi, T.; Mitra, S.; Ernst, P.B.; Crowe, S.E.
    Interleukin-8 induction by Helicobacter pylori in gastric epithelial cells is dependent on apurinic/apyrimidinic endonuclease-1/redox factor-1 (2006), J. Immunol., 177, 7990-7999.
    View publication on PubMed

Application

Application Comment Organism
medicine APE-1/Ref-1 is an important regulator of gastric epithelial responses to Helicobacter pylori infections Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
the APE-1/Ref-1 expression vector pFLAG-APE-1 cDNA3.1 is prepared Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information the enzyme activity of apurinic/apyrimidinic endonuclease is blocked by APE-specific siRNAs Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastric epithelium human gastric epithelial cell line AGS Homo sapiens
-

Synonyms

Synonyms Comment Organism
APE-1
-
Homo sapiens
apurinic/apyrimidinic endonuclease-1
-
Homo sapiens