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Literature summary for 4.2.99.18 extracted from
- Synthesis and characterization of oligonucleotides containing 2'-fluorinated thymidine glycol as inhibitors of the endonuclease III reaction (2006), Nucleic Acids Res., 34, 1540-1551.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| oligonucleotide containing 2'-fluorinated 5R- or 5S-thymidine glycol | inhibits DNA glycosylase activity, not the AP lyase step, in the Endo III reaction, by stabilizing the glycosidic bond | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA containing apurinic/apyrimidinic sites | the enzyme forms a Schiff base-type intermediate with the substrate after the damaged base is removed | Escherichia coli | fragments of DNA | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Endo III | - |
Escherichia coli |
| endonuclease III | - |
Escherichia coli |
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