Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 50% activity at 40 mM | Streptococcus mutans | |
EDTA | 90% inhibition at 0.1 mM | Streptococcus mutans |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | optimal concentration at 5-30 mM, only 50% activity at 40 mM | Streptococcus mutans | |
Mg2+ | stimulates | Streptococcus mutans | |
Mg2+ | optimal concentration: 2.5-30 mM | Streptococcus mutans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | Streptococcus mutans | - |
fragments of DNA | - |
? | |
DNA | Streptococcus mutans UA159 | - |
fragments of DNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus mutans | - |
and strain UR100, activity is present at greater levels in cells grown at low pH than grown at pH 7 | - |
Streptococcus mutans UA159 | - |
and strain UR100, activity is present at greater levels in cells grown at low pH than grown at pH 7 | - |
Purification (Comment) | Organism |
---|---|
500fold | Streptococcus mutans |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
specific activity in the picomolar range | Streptococcus mutans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | - |
Streptococcus mutans | fragments of DNA | - |
? | |
DNA | enzyme has a 3' to 5' exonuclease activity and shows additional functional similarities to DNA repair enzymes | Streptococcus mutans | fragments of DNA | - |
? | |
DNA | specific for apurinic sites | Streptococcus mutans | fragments of DNA | - |
? | |
DNA | - |
Streptococcus mutans UA159 | fragments of DNA | - |
? | |
DNA | enzyme has a 3' to 5' exonuclease activity and shows additional functional similarities to DNA repair enzymes | Streptococcus mutans UA159 | fragments of DNA | - |
? | |
DNA | specific for apurinic sites | Streptococcus mutans UA159 | fragments of DNA | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Streptococcus mutans |