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Literature summary for 4.2.99.18 extracted from

  • Grosch, S.; Kaina, B.
    Transcriptional activation of apurinic/apyrimidinic endonuclease (Ape, Ref-1) by oxidative stress requires CREB (1999), Biochem. Biophys. Res. Commun., 261, 859-863.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information oxidative stress enhances enzyme activity by activation of the APE promoter Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA Homo sapiens
-
fragments of DNA
-
?
additional information Homo sapiens multifunctional enzyme involved in DNA repair and redox regulation of transcription factors ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA
-
Homo sapiens fragments of DNA
-
?
additional information multifunctional enzyme involved in DNA repair and redox regulation of transcription factors Homo sapiens ?
-
?