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Literature summary for 4.2.99.18 extracted from
- Properties of a human lymphoblast AP-endonuclease asociated with activity for DAN damaged by ultraviolet light, gamma-rays, or osmium tetroxide (1983), Biochemistry, 22, 4507-4512.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | endonuclease B has an absolute requirement for Mg2+ | Homo sapiens |  |
| Mg2+ | endonuclease A does not require Mg2+ for full activity | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA | Homo sapiens | - |
fragments of DNA | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
endonuclease A | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial, endonuclease A | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lymphoblast | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA | - |
Homo sapiens | fragments of DNA | - |
? | |
| DNA | endonuclease A: activity for UV-irradiated DNA, gamma-irradiated DNA and OsO4-treated DNA | Homo sapiens | fragments of DNA | - |
? | |
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