Inhibitors | Comment | Organism | Structure |
---|---|---|---|
DL-2-amino-3[(phosphonomethyl)thio]propionic acid | Ki: 0.057 mM, kinact: 1.44 min-1 | Escherichia coli | |
DL-E-2-amino-5-phosphono-4-pentenoic acid | Ki: 0.54 mM | Escherichia coli | |
L-2,3-methanohomoserine phosphate | Ki: 0.01 mM | Escherichia coli | |
L-2-amino-3[(phosphonomethyl)thio]propionic acid | Ki: 0.011 mM | Escherichia coli | |
L-3-hydroxyhomoserine | Ki: 0.05 mM | Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.5 | - |
O-phosphohomoserine | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
O-phospho-L-homoserine + H2O = L-threonine + phosphate | mechanism | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DL-3-chloroalanine | beta-elimination | Escherichia coli | pyruvate + NH3 + HCl | - |
ir | |
DL-vinylglycine + H2O | - |
Escherichia coli | L-threonine | - |
ir | |
L-allo-threonine + H2O | beta-elimination | Escherichia coli | 2-oxobutyrate + NH3 | - |
ir | |
L-serine | beta-elimination | Escherichia coli | pyruvate + NH3 | - |
ir | |
additional information | half-transamination reactions | Escherichia coli | ? | - |
? | |
threonine | beta-elimination | Escherichia coli | 2-oxobutyrate + NH3 | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
7.33 | - |
O-phosphohomoserine | - |
Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | - |
L-2,3-methanohomoserine phosphate | - |
Escherichia coli | |
0.011 | - |
L-2-amino-3[(phosphonomethyl)thio]propionic acid | - |
Escherichia coli | |
0.05 | - |
L-3-hydroxyhomoserine | - |
Escherichia coli | |
0.057 | - |
DL-2-amino-3[(phosphonomethyl)thio]propionic acid | kinact: 1.44 min-1 | Escherichia coli | |
0.54 | - |
DL-E-2-amino-5-phosphono-4-pentenoic acid | - |
Escherichia coli |