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Literature summary for 4.2.3.1 extracted from

  • Madison, J.T.; Thompson, J.F.
    Threonine synthetase from higher plants: stimulation by S-adenosylmethionine and inhibition by cysteine (1976), Biochem. Biophys. Res. Commun., 71, 684-691.
    View publication on PubMed
Search for more literature for 4.2.3.1

Activating Compound

Activating Compound Comment Organism Structure
S-adenosylmethionine allosteric activator, 14fold increase of Vmax, 8% decrease of substrate Km at 0.5 mM Beta vulgaris

Inhibitors

Inhibitors Comment Organism Structure
L-cysteine stereospecific, inhibits S-adenosylmethionine activation Beta vulgaris

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3 2.7 O-phosphohomoserine
-
 Beta vulgaris
1.3 2.7 O-phosphohomoserine
-
 Raphanus sativus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
O-phospho-L-homoserine Beta vulgaris involved in allocation of phosphohomoserine between cystathione and threonine pathways ?
-
 ?

Organism

Organism UniProt Comment Textmining
Beta vulgaris
-
 var. altissima
-
Raphanus sativus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Beta vulgaris
-
leaf
-
 Raphanus sativus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
O-phospho-L-homoserine involved in allocation of phosphohomoserine between cystathione and threonine pathways Beta vulgaris ?
-
 ?
O-phospho-L-homoserine + H2O
-
 Beta vulgaris L-threonine + phosphate
-
 ir
O-phospho-L-homoserine + H2O
-
 Raphanus sativus L-threonine + phosphate
-
 ir

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 enzyme assay at Beta vulgaris

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.3
-
 enzyme assay at Beta vulgaris