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Literature summary for 4.2.1.75 extracted from

  • Alwan, A.F.; Jordan, P.M.
    Isolation of uroporphyrinogen III synthase from Escherichia coli (1988), Biochem. Soc. Trans., 16, 965-966.
No PubMed abstract available
Search for more literature for 4.2.1.75

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01 0.02 Hydroxymethylbilane
-
 Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no requirement Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
26000
-
 SDS-PAGE Escherichia coli
27890
-
 nucleotide sequence Escherichia coli
29000
-
 gel filtration Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Hydroxymethylbilane Escherichia coli synthesis of uroporphyrinogen III, key intermediate for biosynthesis of tetrapyrrolic compounds like chlorophylls, hemes, cytochromes and vitamin B12 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Hydroxymethylbilane
-
 Escherichia coli Uroporphyrinogen III
-
 ?
Hydroxymethylbilane synthesis of uroporphyrinogen III, key intermediate for biosynthesis of tetrapyrrolic compounds like chlorophylls, hemes, cytochromes and vitamin B12 Escherichia coli ?
-
 ?

Subunits

Subunits Comment Organism
monomer SDS-PAGE, gel filtration, nucleotide sequence Escherichia coli

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
additional information
-
 extremely heat labile Escherichia coli