Cloned (Comment) | Organism |
---|---|
overexpression in Escherichia coli, His-tag | Drosophila melanogaster |
Protein Variants | Comment | Organism |
---|---|---|
additional information | isoform IRP-1A specific overexpression in muscle results in pre-adult lethality | Drosophila melanogaster |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Drosophila melanogaster | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
100000 | - |
x * 100000, SDS-PAGE | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | Q9NFX2 | isoforms IRP-1B, the isoform shows aconitase activity, but does not bind to iron-responsive elements | - |
Drosophila melanogaster | Q9NFX3 | isoforms IRP-1A, the isoform shows aconitase activity, and additionally binds to iron-responsive elements | - |
Purification (Comment) | Organism |
---|---|
recombinant protein | Drosophila melanogaster |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cis-aconitate + H2O | - |
Drosophila melanogaster | isocitrate | - |
? | |
additional information | isoform IRP-1A binds in vitro both Drosophila ferritin iron-responsive element and human ferritin iron-responsive element in the presence of a reducing agent | Drosophila melanogaster | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 100000, SDS-PAGE | Drosophila melanogaster |