Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.1.24 extracted from

  • Coates, L.; Beaven, G.; Erskine, P.T.; Beale, S.I.; Avissar, Y.J.; Gill, R.; Mohammed, F.; Wood, S.P.; Shoolingin-Jordan, P.; Cooper, J.B.
    The X-ray structure of the plant like 5-aminolaevulinic acid dehydratase from Chlorobium vibrioforme complexed with the inhibitor laevulinic acid at 2.6 A resolution (2004), J. Mol. Biol., 342, 563-570.
    View publication on PubMed
Search for more literature for 4.2.1.24

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Prosthecochloris vibrioformis

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop method, enzyme complexed with the inhibitor laevulinic acid at 2.6 A resolution, unit cell parameters: a = 125.24 A, b = 125.24 A, c = 164.6 A and spec group P42(1)2 Prosthecochloris vibrioformis

Inhibitors

Inhibitors Comment Organism Structure
laevulinic acid
-
 Prosthecochloris vibrioformis

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ stimulates but is not required for activity. Eight Mg2+ ions can be seen in the crystal structure, one per monomer, all bound at the allosteric magnesium-binding site. No metal ion can be seen in the active site Prosthecochloris vibrioformis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Prosthecochloris vibrioformis early enzyme of the tetrapyrrole biosynthesis pathway ?
-
 ?

Organism

Organism UniProt Comment Textmining
Prosthecochloris vibrioformis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Prosthecochloris vibrioformis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information early enzyme of the tetrapyrrole biosynthesis pathway Prosthecochloris vibrioformis ?
-
 ?