Literature summary for 4.2.1.24 extracted from

Erskine, P.T.; Coates, L.; Newbold, R.; Brindley, A.A.; Stauffer, F.; Beaven, G.D.; Gill, R.; Coker, A.; Wood, S.P.; Warren, M.J.; Shoolingin-Jordan, P.M.; Neier, R.; Cooper, J.B.
Structure of yeast 5-aminolaevulinic acid dehydratase complexed with the inhibitor 5-hydroxylaevulinic acid (2005), Acta Crystallogr. Sect. D, 61, 1222-1226.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
the X-ray structure of the enzyme complexed with the competitive inhibitor 5-hydroxylaevulinic acid, determined at a 1.9 A resolution	Saccharomyces cerevisiae

Inhibitors

Inhibitors	Comment	Organism	Structure
5-hydroxylaevulinic acid	the competitive inhibitor is bound by a Schiff-base link to one of the invariant active-site lysine residues (Lys263). The inhibitor appears to bind in two well defined conformations	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P05373	-	-

Synonyms

Synonyms	Comment	Organism
ALAD	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)