KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.07 | - |
indole | cosubstrate L-Ser | Saccharomyces cerevisiae | |
0.17 | - |
indole | cosubstrate D-glyceraldehyde 3-phosphate | Saccharomyces cerevisiae | |
1.1 | - |
D-glyceraldehyde 3-phosphate | cosubstrate L-Trp, i.e. reverse reaction | Saccharomyces cerevisiae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
77000 | - |
2 * 77000, sedimentation equilibrium in 6 M guanidine hydrochloride | Saccharomyces cerevisiae |
153000 | - |
sedimentation equilibrium centrifugation | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Saccharomyces cerevisiae |
Storage Stability | Organism |
---|---|
-18°C | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-(indol-3-yl)glycerol 3-phosphate + L-serine | r | Saccharomyces cerevisiae | L-tryptophan + D-glyceraldehyde 3-phosphate + H2O | - |
? | |
indole + D-glyceraldehyde 3-phosphate | r | Saccharomyces cerevisiae | indole-3-glycerol phosphate | r | ? | |
indole + L-serine | - |
Saccharomyces cerevisiae | L-tryptophan + H2O | - |
? | |
indole-3-glycerol phosphate | r | Saccharomyces cerevisiae | indole + D-glyceraldehyde 3-phosphate | r | ? | |
L-tryptophan + D-glyceraldehyde 3-phosphate + H2O | r | Saccharomyces cerevisiae | indole-3-glycerol phosphate + L-serine | r | ? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 77000, sedimentation equilibrium in 6 M guanidine hydrochloride | Saccharomyces cerevisiae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
- |
Saccharomyces cerevisiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | Km: 0.18 mM | Saccharomyces cerevisiae |