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Literature summary for 4.2.1.18 extracted from

  • Loupatty, F.J.; Ruiter, J.P.N.; Ijlst, L.; Duran, M.; Wanders, R.J.A.
    Direct nonisotopic assay of 3-methylglutaconyl-CoA hydratase in cultured human skin fibroblasts to specifically identify patients with 3-methylglutaconic aciduria type I (2004), Clin. Chem., 50, 1447-1450.
    View publication on PubMed

Application

Application Comment Organism
medicine sensitive and specific enzymatic assay for 3-methylglutaconyl-CoA hydratase that enables the rapid enzymatic diagnosis of 3-methylglutaconic aciduria type I in cultured skin fibroblasts without the need for radiochemicals Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
patients with 3-methylglutaconic aciduria type I
-

Source Tissue

Source Tissue Comment Organism Textmining
skin fibroblast cultured Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-3-hydroxy-3-methylglutaryl-CoA
-
Homo sapiens trans-3-methylglutaconyl-CoA + H2O
-
?

Synonyms

Synonyms Comment Organism
3-methylglutaconyl-CoA hydratase
-
Homo sapiens
3MGH
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Homo sapiens