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Literature summary for 4.2.1.1 extracted from
- Cloning, characterization and anion inhibition study of the delta-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii (2014), Bioorg. Med. Chem., 22, 531-537.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5-acetamido-1,3,4-thiadiazole-2-sulfonamide | - |
Conticribra weissflogii |  |
| hydrogen sulfide | - |
Conticribra weissflogii | |
| phenylarsonic acid | - |
Conticribra weissflogii | |
| phenylboronic acid | - |
Conticribra weissflogii | |
| sulfamate | - |
Conticribra weissflogii | |
| sulfamide | - |
Conticribra weissflogii | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32300 | - |
calculated from cDNA | Conticribra weissflogii |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Conticribra weissflogii | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| affinity chromatography | Conticribra weissflogii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CO2 + H2O | - |
Conticribra weissflogii | H2CO3 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TweCA | - |
Conticribra weissflogii |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 20 | - |
assay at | Conticribra weissflogii |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 130000 | - |
CO2 | pH 7.5, 20°C | Conticribra weissflogii | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Conticribra weissflogii |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000009 | - |
phenylboronic acid | pH 7.5, 20°C | Conticribra weissflogii | |
| 0.000048 | - |
sulfamide | pH 7.5, 20°C | Conticribra weissflogii | |
| 0.000076 | - |
phenylarsonic acid | pH 7.5, 20°C | Conticribra weissflogii | |
| 0.000079 | - |
sulfamate | pH 7.5, 20°C | Conticribra weissflogii | |
| 0.000083 | - |
5-acetamido-1,3,4-thiadiazole-2-sulfonamide | pH 7.5, 20°C | Conticribra weissflogii | |
| 0.00009 | - |
hydrogen sulfide | pH 7.5, 20°C | Conticribra weissflogii | |
kcat/KM [mM/s]
| kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 33000 | - |
CO2 | pH 7.5, 20°C | Conticribra weissflogii | |
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