Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cd2+ | replacement of zinc ion with cadmium does not entail significant differences in the catalytic performance of the enzyme | Methanosarcina thermophila | |
Cd2+ | replacement of zinc ion with cadmium does not entail significant differences in the catalytic performance of the enzyme | Conticribra weissflogii | |
Zn2+ | required for activity. Replacement of zinc ion with cadmium does not entail significant differences in the catalytic performance of the enzyme | Methanosarcina thermophila | |
Zn2+ | required for activity. Replacement of zinc ion with cadmium does not entail significant differences in the catalytic performance of the enzyme | Conticribra weissflogii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2CO3 | Methanosarcina thermophila | - |
CO2 + H2O | - |
r | |
H2CO3 | Conticribra weissflogii | - |
CO2 + H2O | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Conticribra weissflogii | - |
- |
- |
Methanosarcina thermophila | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
H2CO3 = CO2 + H2O | reaction mechanism, model of the active site designed on the basis of the X-ray crystal structure, proposed for both metal ions similar reaction pathways consisting in the nucleophilic attack by the metal bound hydroxide to the carbon dioxide with bicarbonate formation, in a next internal rotation of this last fragment, and then in the formation of a species ready for the product removal, overview | Methanosarcina thermophila | |
H2CO3 = CO2 + H2O | reaction mechanism, model of the active site designed on the basis of the X-ray crystal structure, proposed for both metal ions similar reaction pathways consisting in the nucleophilic attack by the metal bound hydroxide to the carbon dioxide with bicarbonate formation, in a next internal rotation of this last fragment, and then in the formation of a species ready for the product removal, overview | Conticribra weissflogii |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2CO3 | - |
Methanosarcina thermophila | CO2 + H2O | - |
r | |
H2CO3 | - |
Conticribra weissflogii | CO2 + H2O | - |
r |
Synonyms | Comment | Organism |
---|---|---|
carbonic anhydrase | - |
Methanosarcina thermophila |
carbonic anhydrase | - |
Conticribra weissflogii |
carbonic anhydrase cambialistic enzyme | - |
Methanosarcina thermophila |
carbonic anhydrase cambialistic enzyme | - |
Conticribra weissflogii |
CDCA1 | - |
Methanosarcina thermophila |
More | the enzyme from Methanosorcina thermophila belongs to the gamma class carbonic anhydrases | Methanosarcina thermophila |
TWCA1 | - |
Conticribra weissflogii |
General Information | Comment | Organism |
---|---|---|
evolution | carbonic anhydrase represents one of the most ancient proteins | Methanosarcina thermophila |
evolution | carbonic anhydrase represents one of the most ancient proteins | Conticribra weissflogii |