Activating Compound | Comment | Organism | Structure |
---|---|---|---|
1-(2-aminoethyl)-piperazine | - |
Candida albicans | |
1-(2-aminoethyl)-piperazine | - |
Cryptococcus neoformans | |
2-(2-aminoethyl)pyridine | - |
Candida albicans | |
2-(2-aminoethyl)pyridine | - |
Cryptococcus neoformans | |
2-pyridyl-methylamine | - |
Candida albicans | |
2-pyridyl-methylamine | - |
Cryptococcus neoformans | |
4-(2-aminoethyl)-morpholine | - |
Candida albicans | |
4-(2-aminoethyl)-morpholine | - |
Cryptococcus neoformans | |
4-amino-L-phenylalanine | - |
Candida albicans | |
4-amino-L-phenylalanine | - |
Cryptococcus neoformans | |
D-Dopa | - |
Cryptococcus neoformans | |
D-Dopa | best activator of CaNce103 | Candida albicans | |
D-His | - |
Candida albicans | |
D-His | - |
Cryptococcus neoformans | |
D-Phe | micromolar affinity for Can2 | Cryptococcus neoformans | |
D-Phe | micromolar affinity for CANce103 | Candida albicans | |
D-Trp | - |
Candida albicans | |
D-Trp | - |
Cryptococcus neoformans | |
dopamine | - |
Candida albicans | |
dopamine | - |
Cryptococcus neoformans | |
histamine | - |
Candida albicans | |
histamine | - |
Cryptococcus neoformans | |
L-adrenaline | - |
Candida albicans | |
L-adrenaline | - |
Cryptococcus neoformans | |
L-Dopa | - |
Cryptococcus neoformans | |
L-Dopa | best activator of CaNce103 | Candida albicans | |
L-His | - |
Candida albicans | |
L-His | - |
Cryptococcus neoformans | |
L-Phe | - |
Candida albicans | |
L-Phe | - |
Cryptococcus neoformans | |
L-Trp | - |
Candida albicans | |
L-Trp | - |
Cryptococcus neoformans | |
L-Trp | best Can2 activator | Cryptococcus neoformans | |
L-Tyr | - |
Candida albicans | |
L-Tyr | - |
Cryptococcus neoformans | |
serotonin | - |
Candida albicans | |
serotonin | - |
Cryptococcus neoformans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
8.2 | - |
CO2 | CaNce103, at 25°C, pH 8.3 in 20 mM Tris buffer and 20 mM NaClO4 | Candida albicans | |
9 | - |
CO2 | Can2, at 25°C, pH 8.3 in 20 mM Tris buffer and 20 mM NaClO4 | Cryptococcus neoformans |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Cryptococcus neoformans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CO2 + H2O | - |
Candida albicans | H2CO3 | - |
r | |
CO2 + H2O | - |
Cryptococcus neoformans | H2CO3 | - |
r |
Synonyms | Comment | Organism |
---|---|---|
Can2 | - |
Cryptococcus neoformans |
CaNce103 | - |
Candida albicans |
carbonic anhydrase | - |
Candida albicans |
carbonic anhydrase | - |
Cryptococcus neoformans |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
390000 | - |
CO2 | Can2, at 25°C, pH 8.3 in 20 mM Tris buffer and 20 mM NaClO4 | Cryptococcus neoformans | |
680000 | - |
CO2 | Can2, at 25°C, pH 8.3 in 20 mM Tris buffer and 20 mM NaClO4, in the presence of 0.01 mM histamine | Cryptococcus neoformans | |
800000 | - |
CO2 | CaNce103, at 25°C, pH 8.3 in 20 mM Tris buffer and 20 mM NaClO4 | Candida albicans | |
2010000 | - |
CO2 | CaNce103, at 25°C, pH 8.3 in 20 mM Tris buffer and 20 mM NaClO4, in the presence of 0.01 mM histamine | Candida albicans |