Protein Variants | Comment | Organism |
---|---|---|
additional information | deletion of central components of the ISC system in addition to IscS leads to an overall decrease in Fe-S cluster enzyme and molybdoenzyme activity in addition to a decrease in the number of Fe-S-dependent thiomodifications of tRNA, based on the fact that some proteins involved in Moco biosynthesis and tRNA thiolation are Fe-S-dependent. Complementation of the ISC deficient strains with the suf operon restores the activity of Fe-S-containing proteins, including the MoaA protein, which is involved in the conversion of 5'-GTP to cyclic pyranopterin monophosphate in the fist step of Moco biosynthesis | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Escherichia coli BW25113 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
MoaA | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme MoaA catalyzes the fist step of molybdenum cofactor (Moco) biosynthesis | Escherichia coli |
physiological function | the MoaA protein is involved in the conversion of 5'-GTP to cyclic pyranopterin monophosphate in the fist step of molybdenum cofactor (Moco) biosynthesis | Escherichia coli |