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Literature summary for 4.1.2.40 extracted from
- D-Tagatose-1,6-bisphosphate aldolase (class I) from Staphylococcus aureus (1982), Methods Enzymol., 90, 228-232.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | no inhibition | Staphylococcus aureus |  |
| NaBH4 | - |
Staphylococcus aureus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.5 | - |
D-tagatose 1,6-diphosphate | - |
Staphylococcus aureus | |
| 2.5 | - |
D-fructose 1,6-diphosphate | - |
Staphylococcus aureus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no divalent metal ion required | Staphylococcus aureus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 37000 | - |
- |
Staphylococcus aureus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus aureus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Staphylococcus aureus |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 19.5 | - |
- |
Staphylococcus aureus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, stable for several months | Staphylococcus aureus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-Fructose 1,6-diphosphate | - |
Staphylococcus aureus | Glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
| D-Psicose 1,6-diphosphate | - |
Staphylococcus aureus | Glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
| D-Sorbose 1,6-diphosphate | - |
Staphylococcus aureus | Glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
| D-Tagatose-1,6-bisphosphate | in the reverse reaction the 1,6-diphosphates of all four D-2-oxohexoses are formed | Staphylococcus aureus | Glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
| additional information | no activity with D-fructose 1-phosphate or L-sorbose 1-phosphate | Staphylococcus aureus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 37000 | Staphylococcus aureus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 7.8 | - |
Staphylococcus aureus |
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Release 2023.1 (January 2023)
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