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Literature summary for 4.1.2.17 extracted from

  • Ghalambor, M.A.; Heath, E.C.
    The metabolism of L-fucose. II. The enzymatic cleavage of L-fuculose 1-phosphate (1962), J. Biol. Chem., 237, 2427-2433.
    View publication on PubMed
Search for more literature for 4.1.2.17

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.7
-
 L-Fuculose 1-phosphate
-
 Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ divalent cation required Escherichia coli
Ca2+ 0.01 M, restores activity after dialysis with EDTA Escherichia coli
Mg2+ divalent cation required Escherichia coli
Mg2+ 0.01 M, restores activity after dialysis with EDTA Escherichia coli
Mn2+ divalent cation required Escherichia coli
Mn2+ 0.01 M, restores activity after dialysis with EDTA Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Fuculose 1-phosphate Escherichia coli initial step in the metabolism of L-fucose ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-Deoxy-L-sorbose 1-phosphate about 5% of the activity with L-fuculose 1-phosphate Escherichia coli ?
-
 ?
D-Fructose 1,6-diphosphate about 4% of the activity with L-fuculose 1-phosphate Escherichia coli ?
-
 ?
D-Fructose 1-phosphate about 4% of the activity with L-fuculose 1-phosphate Escherichia coli ?
-
 ?
D-Ribulose 1,5-diphosphate about 6% of the activity with L-fuculose 1-phosphate Escherichia coli ?
-
 ?
Glycerone phosphate + (R)-lactaldehyde at 73% of the activity with (S)-lactaldehyde Escherichia coli 6-Deoxy-D-psicose 1-phosphate
-
 ?
Glycerone phosphate + (S)-lactaldehyde
-
 Escherichia coli L-Fuculose 1-phosphate
-
 ?
glycerone phosphate + D-glyceraldehyde at 33% of the activity with (S)-lactaldehyde Escherichia coli D-psicose 1-phosphate
-
 ?
Glycerone phosphate + glycolaldehyde at 10% of the activity with (S)-lactaldehyde Escherichia coli D-Ribulose 1-phosphate
-
 ?
glycerone phosphate + L-glyceraldehyde at 33% of the activity with (S)-lactaldehyde Escherichia coli L-tagatose 1-phosphate
-
 ?
L-fuculose 1-phosphate
-
 Escherichia coli glycerone phosphate + (S)-lactaldehyde
-
 ?
L-Fuculose 1-phosphate initial step in the metabolism of L-fucose Escherichia coli ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
-
 Escherichia coli

pH Range

pH Minimum pH Maximum Comment Organism
6.4 8.8 pH 6.4: about 30% of maximal activity, pH 8.8: about 40% of maximal activity Escherichia coli