Literature summary for 4.1.2.13 extracted from

Callens, M.; Kuntz, D.A.; Opperdoes, F.R.
Kinetic properties of fructose bisphosphate aldolase from rabbit muscle and Staphylococcus aureus (1991), Mol. Biochem. Parasitol., 47, 1-10.

Search for more literature for 4.1.2.13

Inhibitors

Inhibitors	Comment	Organism	Structure
diphosphate	-	Trypanosoma brucei
phosphate	-	Trypanosoma brucei

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0088	-	D-fructose 1,6-bisphosphate	pH 7.6	Oryctolagus cuniculus
0.0092	-	D-fructose 1,6-bisphosphate	pH 7.6, native enzyme	Trypanosoma brucei
0.0138	-	D-fructose 1,6-bisphosphate	pH 7.6	Oryctolagus cuniculus
0.0401	-	D-fructose 1,6-bisphosphate	pH 9.3	Staphylococcus aureus
0.0459	-	D-fructose 1,6-bisphosphate	pH 5.5	Oryctolagus cuniculus
0.0552	-	D-fructose 1,6-bisphosphate	pH 9.3	Oryctolagus cuniculus
0.0656	-	D-fructose 1,6-bisphosphate	pH 5.5	Staphylococcus aureus
0.0728	-	D-fructose 1,6-bisphosphate	pH 5.5	Trypanosoma brucei
0.0777	-	D-fructose 1,6-bisphosphate	pH 9.2	Trypanosoma brucei
1.6	-	fructose 1-phosphate	pH 5.5	Oryctolagus cuniculus
1.9	-	fructose 1-phosphate	pH 5.5	Trypanosoma brucei
3.8	-	fructose 1-phosphate	pH 5.5	Staphylococcus aureus
5.3	-	fructose 1-phosphate	pH 7.6	Oryctolagus cuniculus
6.2	-	fructose 1-phosphate	pH 7.6	Trypanosoma brucei
9	-	fructose 1-phosphate	pH 9.2	Trypanosoma brucei
11	-	fructose 1-phosphate	pH 9.3	Oryctolagus cuniculus
11.3	-	fructose 1-phosphate	pH 7.6	Staphylococcus aureus
18	-	fructose 1-phosphate	pH 9.3	Staphylococcus aureus

Organism

Organism	UniProt	Comment	Textmining
Oryctolagus cuniculus	-	-	-
Staphylococcus aureus	-	-	-
Trypanosoma brucei	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
muscle	-	Oryctolagus cuniculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-fructose 1,6-bisphosphate	-	Staphylococcus aureus	glycerone phosphate + D-glyceraldehyde 3-phosphate	-	?
D-fructose 1,6-bisphosphate	-	Oryctolagus cuniculus	glycerone phosphate + D-glyceraldehyde 3-phosphate	-	?
D-fructose 1,6-bisphosphate	-	Trypanosoma brucei	glycerone phosphate + D-glyceraldehyde 3-phosphate	-	?
D-Fructose 1-phosphate	-	Staphylococcus aureus	Glycerone phosphate + D-glyceraldehyde	-	?
D-Fructose 1-phosphate	-	Oryctolagus cuniculus	Glycerone phosphate + D-glyceraldehyde	-	?
D-Fructose 1-phosphate	-	Trypanosoma brucei	Glycerone phosphate + D-glyceraldehyde	-	?

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.167	-	fructose 1-phosphate	pH 9.3	Oryctolagus cuniculus
0.183	-	fructose 1-phosphate	pH 5.5	Oryctolagus cuniculus
0.267	-	fructose 1-phosphate	pH 7.6	Oryctolagus cuniculus
0.45	-	fructose 1-phosphate	pH 5.5	Staphylococcus aureus
0.583	-	fructose 1-phosphate	pH 9.3	Staphylococcus aureus
1.05	-	fructose 1-phosphate	pH 7.6	Staphylococcus aureus
1.13	-	fructose 1-phosphate	pH 5.5	Trypanosoma brucei
1.27	-	fructose 1-phosphate	pH 9.2	Trypanosoma brucei
1.63	-	D-fructose 1,6-bisphosphate	pH 5.5	Oryctolagus cuniculus
1.7	-	fructose 1-phosphate	pH 7.6	Trypanosoma brucei
4.02	-	D-fructose 1,6-bisphosphate	pH 9.3	Oryctolagus cuniculus
5.03	-	D-fructose 1,6-bisphosphate	pH 5.5	Trypanosoma brucei
5.28	-	D-fructose 1,6-bisphosphate	pH 9.2	Trypanosoma brucei
5.47	-	D-fructose 1,6-bisphosphate	pH 7.6	Oryctolagus cuniculus
7.5	-	D-fructose 1,6-bisphosphate	pH 9.3	Staphylococcus aureus
7.87	-	D-fructose 1,6-bisphosphate	pH 5.5	Staphylococcus aureus
10.3	-	D-fructose 1,6-bisphosphate	pH 7.6, native enzyme	Trypanosoma brucei
13.9	-	D-fructose 1,6-bisphosphate	pH 7.6	Staphylococcus aureus

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Release 2023.1 (January 2023)