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Literature summary for 4.1.1.48 extracted from

  • Hoch, S.O.
    Isolation and characterization of two tryptophan biosynthetic enzymes, indoleglycerol phosphate synthase and phosphoribosyl anthranilate isomerase, from Bacillus subtilis (1979), J. Bacteriol., 139, 362-368.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.48

General Stability

General Stability Organism
optimal stabilization by 0.8 M sucrose Bacillus subtilis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
23500
-
 1 * 23500, SDS-PAGE Bacillus subtilis
31000
-
 gel filtration Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate Bacillus subtilis enzyme is involved in tryptophan biosynthesis ?
-
 ?
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate Bacillus subtilis T3 enzyme is involved in tryptophan biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bacillus subtilis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.7
-
-
 Bacillus subtilis

Storage Stability

Storage Stability Organism
4°C, in presence of 0.8 M sucrose, 20% loss of activity Bacillus subtilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate
-
 Bacillus subtilis 1-(3-Indolyl)glycerol-3-phosphate + CO2 + H2O
-
 ?
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate
-
 Bacillus subtilis T3 1-(3-Indolyl)glycerol-3-phosphate + CO2 + H2O
-
 ?
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate enzyme is involved in tryptophan biosynthesis Bacillus subtilis ?
-
 ?
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate enzyme is involved in tryptophan biosynthesis Bacillus subtilis T3 ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 23500, SDS-PAGE Bacillus subtilis