Crystallization (Comment) | Organism |
---|---|
PDB ID 1DQX, free enzyme and enzyme bound to 6-hydroxy-UMP, crystal structure analysis of the enzyme in presence or absence of a potenial transition state analogue, comparison to predicted structure by QM/MM enzyme simulations, overview | Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Orotidine 5'-phosphate | Saccharomyces cerevisiae | - |
UMP + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
orotidine 5'-phosphate = UMP + CO2 | direct decarboxylation mechanism, modeling with 6-carbanion derivatives of uracil analogues, overview | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Orotidine 5'-phosphate | - |
Saccharomyces cerevisiae | UMP + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | QM/MM enzyme simulations, free enzyme and enzyme bound to 6-hydroxy-UMP, QM/MM and metadynamics, enzyme structure analysis, overview | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
orotidine-5-monophosphate decarboxylase | - |
Saccharomyces cerevisiae |