Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | antigen challenge induces HDC in both mast cell-dependent and mast cell-independent ways at a postanaphylactic time in the liver, lung, spleen, and ears, enzyme activity is increased in atissue-dependent manner after sensitization of wild-type mice by ovalbumin, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine | Mus musculus | HDC induction may contribute to the replenishment of the reduced pool of mast cell histamine in the anaphylactic period | histamine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
wild-type BALB/c mice, mast cell-deficient W/W v mice, and IL-1-KO BALB/c mice, deficient in both Iinterleukin-1alpha and interleukin-1beta | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
ear | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
spleen | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine | - |
Mus musculus | histamine + CO2 | - |
? | |
L-histidine | HDC induction may contribute to the replenishment of the reduced pool of mast cell histamine in the anaphylactic period | Mus musculus | histamine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HDC | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Mus musculus |