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Literature summary for 4.1.1.15 extracted from

  • Liu, H.; Li, S.; Zhang, Y.; Yan, Y.; Li, Y.
    Dynamic regulation of glutamic acid decarboxylase 65 gene expression in rat testis (2009), Acta Biochim. Biophys. Sin., 41, 545-553.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
SDS-PAGE, N-terminal 69 amino acids truncated form of full-length GAD65 protein Rattus norvegicus
65000
-
full-length GAD65 protein, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-glutamate Rattus norvegicus
-
4-aminobutanoate + CO2
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Leydig cell
-
Rattus norvegicus
-
spermatid
-
Rattus norvegicus
-
spermatocyte
-
Rattus norvegicus
-
testis the 58-kDa GAD65, N-terminal 69 amino acids truncated form of full-length GAD65 protein, is developmentally expressed during post-natal testis maturation Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate
-
Rattus norvegicus 4-aminobutanoate + CO2
-
?

Synonyms

Synonyms Comment Organism
GAD65
-
Rattus norvegicus
glutamic acid decarboxylase 65
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus GAD65 gene expression is dynamically regulated at multiple levels during post-natal testis maturation, GAD65 protein is presented in Leydig cells of day 1 testis, primary spermatocytes and spermatids of postnatal of day 90 testis up