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Literature summary for 4.1.1.15 extracted from

  • Martyniuk, C.J.; Chang, J.P.; Trudeau, V.L.
    The effects of GABA agonists on glutamic acid decarboxylase, GABA-transaminase, activin, salmon gonadotrophin-releasing hormone and tyrosine hydroxylase mRNA in the goldfish (Carassius auratus) neuroendocrine brain (2007), J. Neuroendocrinol., 19, 390-396.
    View publication on PubMed
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Application

Application Comment Organism
medicine injection of gamma-aminobutanoate agonists baclofen and muscimol increases luteinising hormone in serum after 6 h. Intraperitoneal treatment with gamma-aminobutanaote A agonist muscimol decreases mRNA of isoform GAD65 approximately 10fold, gamma-aminobutanaote transaminase approximately 15fold and tyrosine hydroxylase approximately 3fold in telencephalon. Intraperitoneal treatment with gamma-aminobutanaote B agonist baclofen reduces mRNA levels of isoform GAD67 approximately 2fold and gamma-aminobutanaote transaminase approximately 2fold in hypothalamus Carassius auratus

Organism

Organism UniProt Comment Textmining
Carassius auratus
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Source Tissue

Source Tissue Comment Organism Textmining
brain
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 Carassius auratus
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hypothalamus intraperitoneal treatment with gamma-aminobutanaote B agonist baclofen reduces mRNA levels of isoform GAD67 approximately 2fold and gamma-aminobutanaote transaminase approximately 2fold Carassius auratus
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telencephalon intraperitoneal treatment with gamma-aminobutanaote A agonist muscimol decreases mRNA of isoform GAD65 approximately 10fold, gamma-aminobutanaote transaminase approximately 15fold and tyrosine hydroxylase approximately 3fold Carassius auratus
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