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Literature summary for 4.1.1.15 extracted from

  • Wei, J.; Davis, K.M.; Wu, H.; Wu, J.Y.
    Protein phosphorylation of human brain glutamic acid decarboxylase (GAD)65 and GAD67 and its physiological implications (2004), Biochemistry, 43, 6182-6189.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
T91A abolishes phosphorylation by protein kinase A and subsequent inhibition of enzyme activity Homo sapiens
T91D mimics the inhibiting effect of enzyme phosphorylation Homo sapiens
T91E mimics the inhibiting effect of enzyme phosphorylation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
recombinant isoforms GAD65 and GAD67
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein isoform GAD65 is activated by phosphorylation, GAD67 is inhibited by phosphorylation. Phosphorylation of GAD67 occurs at T91 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining