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Literature summary for 4.1.1.1 extracted from
- Coexpression of pyruvate decarboxylase and alcohol dehydrogenase genes in Lactobacillus brevis (2007), FEMS Microbiol. Lett., 274, 291-297.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | the enzyme is useful in ethanol production in bacterial coupled systems, overview | Sarcina ventriculi |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene pdc, co-expression with Lactobacillus brevis alcohol dehydrogenase in Lactobacillus brevis strain ATCC367 using a Gram-positive promoter, co-expression of both enzymes in Escherichia coli NZN111, a fermentative defective strain incapable of growing anaerobically, restores anaerobic growth and confers ethanol production | Sarcina ventriculi |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | engineering of Lactobacillus brevis strain ATCC367 to express Sarcina ventriculi pyruvate decarboxylase and Lactobacillus brevis alcohol dehydrogenase genes in order to increase ethanol fermentation from biomass-derived residues, the engineered strain is termed bbc03, overview | Sarcina ventriculi |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 58000 | - |
x * 58000, recombinant enzyme, SDS-PAGE | Sarcina ventriculi |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate | Sarcina ventriculi | - |
acetaldehyde + CO2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sarcina ventriculi | - |
gene pdc | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate | - |
Sarcina ventriculi | acetaldehyde + CO2 | - |
? | |
| pyruvate + acetaldehyde | carboligation reaction | Sarcina ventriculi | acetoin + CO2 | - |
? | |
| pyruvate + benzaldehyde | carboligation reaction | Sarcina ventriculi | (R)-phenylacetylcarbinol + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 58000, recombinant enzyme, SDS-PAGE | Sarcina ventriculi |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDC | - |
Sarcina ventriculi |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Sarcina ventriculi |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
assay at | Sarcina ventriculi |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thiamine diphosphate | - |
Sarcina ventriculi | |
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Release 2023.1 (January 2023)
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