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Literature summary for 3.8.1.2 extracted from

  • Wang, Y.; Xin, Y.; Cao, X.; Xue, S.
    Enhancement of L-2-haloacid dehalogenase expression in Pseudomonas stutzeri DEH138 based on the different substrate specificity between dehalogenase-producing bacteria and their dehalogenases (2015), World J. Microbiol. Biotechnol., 31, 669-673.
    View publication on PubMed
Search for more literature for 3.8.1.2

Application

Application Comment Organism
additional information L-2-haloacid dehalogenase acts specifically on L-2-haloalkanoic acids to produce D-2-hydroxyalkanoic acids, which have potential applications in chemical industries and bioremediation Pseudomonas stutzeri

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-chloropropionate + H2O Pseudomonas stutzeri
-
 2-hydroxypropionate + chloride
-
 ?
2-chloropropionate + H2O Pseudomonas stutzeri DEH138
-
 2-hydroxypropionate + chloride
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas stutzeri
-
 isolated from the intertidal marine sponge Hymeniacidon perlevis
-
Pseudomonas stutzeri DEH138
-
 isolated from the intertidal marine sponge Hymeniacidon perlevis
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information the organism is capable of using 2-chloropropionate, dichloroacetate, monochloroacetate, monobromoacetate, monoiodoacetate, DL-2-chloropropionate, and DL-2-bromopropionate as sole carbon source, 2-chloropropionate induces the expression of the enzyme, optimization of enzyme production, overview Pseudomonas stutzeri
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-chloropropionate + H2O
-
 Pseudomonas stutzeri 2-hydroxypropionate + chloride
-
 ?
2-chloropropionate + H2O
-
 Pseudomonas stutzeri DEH138 2-hydroxypropionate + chloride
-
 ?
dichloroacetate + H2O
-
 Pseudomonas stutzeri ?
-
 ?
dichloroacetate + H2O
-
 Pseudomonas stutzeri DEH138 ?
-
 ?
DL-2-bromobutyrate + H2O
-
 Pseudomonas stutzeri ?
-
 ?
DL-2-bromobutyrate + H2O
-
 Pseudomonas stutzeri DEH138 ?
-
 ?
DL-2-bromopropionate + H2O
-
 Pseudomonas stutzeri ?
-
 ?
DL-2-chlorobutyrate + H2O
-
 Pseudomonas stutzeri ?
-
 ?
DL-2-chloropropionate + H2O
-
 Pseudomonas stutzeri ?
-
 ?
DL-2-chloropropionate + H2O
-
 Pseudomonas stutzeri DEH138 ?
-
 ?
L-2-chloropropionate + H2O
-
 Pseudomonas stutzeri D-2-hydroxypropionate + chloride
-
 ?
monobromoacetate + H2O
-
 Pseudomonas stutzeri hydroxyacetate + bromide
-
 ?
monochloroacetate + H2O
-
 Pseudomonas stutzeri hydroxyacetate + chloride
-
 ?
monoiodoacetate + H2O
-
 Pseudomonas stutzeri hydroxyacetate + iodide
-
 ?
additional information L-2-haloacid dehalogenase acts specifically on L-2-haloalkanoic acids to produce D-2-hydroxyalkanoic acids, which have potential applications in chemical industries and bioremediation. No activity with DL-2-fluopropionate, 3-chloropropionate, 2,2-dichloropropionate, DL-2-chloropropionamide, and DL-2-bromopropionamide Pseudomonas stutzeri ?
-
 ?
additional information L-2-haloacid dehalogenase acts specifically on L-2-haloalkanoic acids to produce D-2-hydroxyalkanoic acids, which have potential applications in chemical industries and bioremediation. No activity with DL-2-fluopropionate, 3-chloropropionate, 2,2-dichloropropionate, DL-2-chloropropionamide, and DL-2-bromopropionamide Pseudomonas stutzeri DEH138 ?
-
 ?

Synonyms

Synonyms Comment Organism
L-2-haloacid dehalogenase
-
 Pseudomonas stutzeri
L-DEX
-
 Pseudomonas stutzeri