Application | Comment | Organism |
---|---|---|
medicine | xanthurenic aciduria is linked to a mutation in the gene encoding kynureninase | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
T198A | screening of cDNA from KYNU revealed homozygosity for a c.593A>G substitution in exon 7 in the proband, leading to a threonine-to-alanine shift, T198A, in kynureninase | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + H2O | Homo sapiens | - |
anthranilate + L-alanine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | the catalytic activity of kynureninase is very low in most tissue with exception of liver and kidney | Homo sapiens | - |
liver | the catalytic activity of kynureninase is very low in most tissue with exception of liver and kidney | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + H2O | - |
Homo sapiens | anthranilate + L-alanine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
kynureninase | - |
Homo sapiens |