Literature summary for 3.7.1.3 extracted from

Pellicciari, R.; Rizzo, R.C.; Costantino, G.; Marinozzi, M.; Amori, L.; Guidetti, P.; Wu, H.; Schwarcz, R.
Modulators of the kynurenine pathway of tryptophan metabolism: synthesis and preliminary biological evaluation of (S)-4-(ethylsulfonyl)benzoylalanine, a potent and selective kynurenine aminotransferase II (KAT II) inhibitor (2006), ChemMedChem, 1, 528-531.

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Inhibitors

Inhibitors	Comment	Organism	Structure
DL-5-chloro-kynurenine	substantially inhibits	Rattus norvegicus
L-5-chloro-kynurenine	substantially inhibits	Rattus norvegicus
additional information	not inhibited by DL-4-(ethylsulfonyl)benzoylalanine and its active enatiomer (S)-4-(ethylsulfonyl)benzoylalanine	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

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Release 2023.1 (January 2023)