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Literature summary for 3.6.4.13 extracted from

  • Schuetz, P.; Wahlberg, E.; Karlberg, T.; Hammarstroem, M.; Collins, R.; Flores, A.; Schueler, H.
    Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein (2010), J. Mol. Biol., 400, 768-782.
    View publication on PubMed
Search for more literature for 3.6.4.13

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting-drop vapor diffusion method at 4 °C. Crystal structures of the conserved domain 1 of the DEIH-motif-containing helicase DHX9 and of the DEAD-box helicase DDX20. Both contain a RecA-like core, but DHX9 differs from DEAD-box proteins in the arrangement of secondary structural elements and is more similar to viral helicases such as NS3. The N-terminus of the DHX9 core contains two long alpha-helices that reside on the surface of the core without contributing to nucleotide binding Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q08211
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Homo sapiens ADP + phosphate
-
 ?
CTP + H2O
-
 Homo sapiens CDP + phosphate
-
 ?
GTP + H2O
-
 Homo sapiens GDP + phosphate
-
 ?
UTP + H2O
-
 Homo sapiens UDP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
DHX9
-
 Homo sapiens
RNA helicase A
-
 Homo sapiens