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Literature summary for 3.6.1.6 extracted from

  • Martin-Satue, M.; Lavoie, E.G.; Pelletier, J.; Fausther, M.; Csizmadia, E.; Guckelberger, O.; Robson, S.C.; Sevigny, J.
    Localization of plasma membrane bound NTPDases in the murine reproductive tract (2009), Histochem. Cell Biol., 131, 615-628.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.6

Cloned(Commentary)

Cloned (Comment) Organism
expression of NTPDase1, NTPDase2, and NTPDase3 in COS-7 cells Mus musculus
expression of NTPDase1, NTPDase2, and NTPDase3 in COS-7 cells Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
additional information NTPDase activities are increased in Entpd1-deficient mice Mus musculus
additional information NTPDase activities are increased in Entpd1-deficient mice Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus Golgi-phase acrosome, NTPDase6 Mus musculus 5794
-
Golgi apparatus Golgi-phase acrosome, NTPDase6 Rattus norvegicus 5794
-
additional information subcellular localization of isozymes, overview Mus musculus
-
-
additional information subcellular localization of isozymes, overview Rattus norvegicus
-
-
plasma membrane bound Mus musculus 5886
-
plasma membrane bound Rattus norvegicus 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+
-
 Mus musculus
Mn2+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Mus musculus
-
 ADP + phosphate
-
 ?
ATP + H2O Rattus norvegicus
-
 ADP + phosphate
-
 ?
ATP + H2O Mus musculus C57BL/6
-
 ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 C57BL/6 mice
-
Mus musculus C57BL/6
-
 C57BL/6 mice
-
Rattus norvegicus
-
 Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
blood vessel oviductal and uterine, endothelium, NTPDase1 is located especially in the lamina propria mucosae and uterine blood vessel endothelium Mus musculus
-
blood vessel oviductal and uterine, endothelium, NTPDase1 is located especially in the lamina propria mucosae and uterine blood vessel endothelium Rattus norvegicus
-
connective tissue NTPDase3 Mus musculus
-
connective tissue NTPDase3 Rattus norvegicus
-
epididymis epithelium, NTPDase1 Mus musculus
-
epididymis epithelium, NTPDase1 Rattus norvegicus
-
epithelium NTPDase1 in epididymal, NTPDase3 in secretory Mus musculus
-
epithelium NTPDase1 in epididymal, NTPDase3 in secretory Rattus norvegicus
-
macrophage interstitial, NTPDase1 Mus musculus
-
macrophage interstitial, NTPDase1 Rattus norvegicus
-
additional information tissue localization of isozymes, overview Mus musculus
-
additional information tissue localization of isozymes, overview Rattus norvegicus
-
ovarian granulosa cell NTPDase1 Mus musculus
-
ovarian granulosa cell NTPDase1 Rattus norvegicus
-
oviduct
-
 Mus musculus
-
oviduct
-
 Rattus norvegicus
-
prostate parenchyma, NTPDase1 and NTPDase2, the latter in association with connective tissue. NTPDase3 is located in the apical pole of the epithelial cells lining the lumen of the secretory portion of the prostate gland Mus musculus
-
prostate parenchyma, NTPDase1 and NTPDase2, the latter in association with connective tissue. NTPDase3 is located in the apical pole of the epithelial cells lining the lumen of the secretory portion of the prostate gland Rattus norvegicus
-
Sertoli cell NTPDase1 Mus musculus
-
Sertoli cell NTPDase1 Rattus norvegicus
-
smooth muscle of tunica muscularis and blood vessels of the muscular layer of oviductal serosa, NTPDase1 Mus musculus
-
smooth muscle of tunica muscularis and blood vessels of the muscular layer of oviductal serosa, NTPDase1 Rattus norvegicus
-
spermatid round, NTPDase6 Mus musculus
-
spermatid round, NTPDase6 Rattus norvegicus
-
testis NTPDase1 Mus musculus
-
testis NTPDase1 Rattus norvegicus
-
vascular endothelial cell
-
 Mus musculus
-
vascular endothelial cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Mus musculus ADP + phosphate
-
 ?
ATP + H2O
-
 Rattus norvegicus ADP + phosphate
-
 ?
ATP + H2O
-
 Mus musculus C57BL/6 ADP + phosphate
-
 ?
additional information NTPDase1 hydrolyzes ATP and ADP at a similar rate Mus musculus ?
-
 ?
additional information NTPDase1 hydrolyzes ATP and ADP at a similar rate Rattus norvegicus ?
-
 ?
additional information NTPDase1 hydrolyzes ATP and ADP at a similar rate Mus musculus C57BL/6 ?
-
 ?

Synonyms

Synonyms Comment Organism
CD39
-
 Mus musculus
CD39
-
 Rattus norvegicus
ectonucleoside triphosphate diphosphohydrolase
-
 Mus musculus
ectonucleoside triphosphate diphosphohydrolase
-
 Rattus norvegicus
More the enzyme belongs to the ectonucleoside triphosphate diphosphohydrolase, E-NTPDase, family Mus musculus
More the enzyme belongs to the ectonucleoside triphosphate diphosphohydrolase, E-NTPDase, family Rattus norvegicus
NTPDase1
-
 Mus musculus
NTPDase1
-
 Rattus norvegicus
NTPDase2
-
 Mus musculus
NTPDase2
-
 Rattus norvegicus
NTPDase3
-
 Mus musculus
NTPDase3
-
 Rattus norvegicus
NTPDase6
-
 Mus musculus
NTPDase6
-
 Rattus norvegicus
NTPDase8
-
 Mus musculus
NTPDase8
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
 assay at Mus musculus
7.6
-
 assay at Rattus norvegicus