Literature summary for 3.5.4.4 extracted from

Hitoglou, S.; Zournatzi, V.; Gougoustamou, D.; Hatzistilianou, M.; Tzafettas, J.
Adenosine deaminase activity and its isoenzyme pattern in women with recurrent spontaneous abortions (2004), Gynecol. Obstet. Invest., 58, 126-129.

Search for more literature for 3.5.4.4

Inhibitors

Inhibitors	Comment	Organism	Structure
erythro-9-(2-hydroxy-3-nonyl)adenine	i.e. EHNA	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	blood serum	Homo sapiens	-	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
adenosine + H2O	Homo sapiens	the enzyme expression and activity is suppressed in normal pregnancy, but not in woman with recurrent spontaneous abortion	inosine + NH3	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	female, isozymes ADA1 and ADA2	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood serum	-	Homo sapiens	-
lymphocyte	peripheral blood	Homo sapiens	-
placenta	trophoblast, enzyme activity and its isoenzyme pattern in women with recurrent spontaneous abortions	Homo sapiens	-
trophoblast	differentiating	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
adenosine + H2O	-	Homo sapiens	inosine + NH3	-	?
adenosine + H2O	the enzyme expression and activity is suppressed in normal pregnancy, but not in woman with recurrent spontaneous abortion	Homo sapiens	inosine + NH3	-	?

Synonyms

Synonyms	Comment	Organism
ADA	-	Homo sapiens

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Release 2023.1 (January 2023)