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Literature summary for 3.5.3.15 extracted from
- Kinetics of human peptidylarginine deiminase 2 (hPAD2)--reduction of Ca2+ dependence by phospholipids and assessment of proposed inhibition by paclitaxel side chains (2008), Biochem. Cell Biol., 86, 437-447.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | the methyl ester side chain of paclitaxel alone does not inhibit activity of PAD2 | Homo sapiens |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent on, phoshatidylserine and phosphatidylcholine reduce the Ca2+-dependence by almost 2fold | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzoyl-L-Arg ethyl ester + H2O | - |
Homo sapiens | benzoyl-L-citrulline ethyl ester + NH3 | - |
? | |
| myelin basic protein L-arginine + H2O | - |
Homo sapiens | myelin basic protein L-citrulline + NH3 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PAD2 | - |
Homo sapiens |
| peptidylarginine deiminase 2 | - |
Homo sapiens |
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