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Literature summary for 3.5.3.15 extracted from

  • Jang, B.; Kim, E.; Choi, J.K.; Jin, J.K.; Kim, J.I.; Ishigami, A.; Maruyama, N.; Carp, R.I.; Kim, Y.S.; Choi, E.K.
    Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis (2008), Am. J. Pathol., 173, 1129-1142.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.3.15

Organism

Organism UniProt Comment Textmining
Mus musculus Q08642
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte PAD2 immunoreactivity is increased in Scrapie-infected brains, with staining detected primarily in reactive astrocytes Mus musculus
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brain expression levels of PAD2 protein as well as its enzyme activity are significantly increased in brain sections of Scrapie-infected mice, including hippocampus, brain stem, and striatum Mus musculus
-
brain stem
-
 Mus musculus
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cerebellum
-
 Mus musculus
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cerebral cortex
-
 Mus musculus
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corpus striatum
-
 Mus musculus
-
hippocampus
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
aldolase 1A L-Arg + H2O
-
 Mus musculus aldolase 1A L-citrulline + NH3
-
 ?
aldolase 3C L-Arg + H2O
-
 Mus musculus aldolase 3C L-citrulline + NH3
-
 ?
aldolase C L-Arg + H2O
-
 Mus musculus aldolase C L-citrulline + NH3
-
 ?
alpha-enolase 1 L-Arg + H2O
-
 Mus musculus alpha-enolase 1 L-citrulline + NH3
-
 ?
benzoyl-L-arginine ethyl ester + H2O
-
 Mus musculus benzoyl-L-citrulline ethyl ester + NH3
-
 ?
beta2-tubulin L-Arg + H2O
-
 Mus musculus beta2-tubulin L-citrulline + NH3
-
 ?
glial fibrillary acidic protein-L-Arg + H2O
-
 Mus musculus glial fibrillary acidic protein-L-citrulline + NH3
-
 ?
heat shock protein 8 L-Arg + H2O
-
 Mus musculus heat shock protein 8 L-citrulline + NH3
-
 ?
myelin basic protein-L-Arg + H2O
-
 Mus musculus myelin basic protein-L-citrulline + NH3
-
 ?
neuron-specific enolase 2 L-Arg + H2O
-
 Mus musculus neuron-specific enolase 2 L-citrulline + NH3
-
 ?
peptidylprolyl isomerase A L-Arg + H2O
-
 Mus musculus peptidylprolyl isomerase A L-citrulline + NH3
-
 ?
peroxiredoxin 1 L-Arg + H2O
-
 Mus musculus peroxiredoxin 1 L-citrulline + NH3
-
 ?
voltage-dependent anion channel 1 L-Arg + H2O
-
 Mus musculus voltage-dependent anion channel 1 L-citrulline + NH3
-
 ?
[cofilin 1]-L-Arg + H2O
-
 Mus musculus [cofilin 1]-L-citrulline + NH3
-
 ?
[mitochondrial malate dehydrogenase 2]-L-arginine + H2O
-
 Mus musculus [mitochondrial malate dehydrogenase 2]-L-citrulline + NH3
-
 ?

Synonyms

Synonyms Comment Organism
PAD2
-
 Mus musculus
peptidylarginine deiminase 2
-
 Mus musculus