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Literature summary for 3.5.3.15 extracted from
- Expression pattern of peptidylarginine deiminase in rat and human Schwann cells (2007), Dev. Neurobiol., 68, 101-114.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression analysis | Homo sapiens |
| expression analysis | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | PAD3, exclusively | Homo sapiens | 5634 | - |
| nucleus | PAD3, exclusively | Rattus norvegicus | 5634 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent on | Homo sapiens |  |
| Ca2+ | dependent on | Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protein-L-arginine + H2O | Homo sapiens | citrullination of proteins may exert a specific role in the course of PNS development and repair | protein-L-citrulline + NH3 | - |
? | |
| protein-L-arginine + H2O | Rattus norvegicus | citrullination of proteins may exert a specific role in the course of PNS development and repair | protein-L-citrulline + NH3 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Homo sapiens | Q9ULC6 | PAD1 | - |
| Homo sapiens | Q9Y2J8 | PAD2 | - |
| Rattus norvegicus | - |
female and male Wistar rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebellum | - |
Rattus norvegicus | - |
| cerebellum | - |
Homo sapiens | - |
| cerebellum | high amount of PAD2 | Homo sapiens | - |
| dermis | - |
Rattus norvegicus | - |
| dermis | high amount of PAD2 | Homo sapiens | - |
| additional information | PAD tissue expression pattern, overview | Homo sapiens | - |
| additional information | PAD tissue expression pattern, overview | Rattus norvegicus | - |
| nerve | fetal, increased amounts of PAD3 | Homo sapiens | - |
| nerve | juvenile, increased amounts of PAD3 | Rattus norvegicus | - |
| oligodendrocyte | PAD2 | Rattus norvegicus | - |
| oligodendrocyte | PAD2 | Homo sapiens | - |
| Schwann cell | - |
Homo sapiens | - |
| Schwann cell | majority of PAD2 staining in immature cell stages, overview | Rattus norvegicus | - |
| Schwann cell | majority of PAD2 staining in immature cell stages, overview | Homo sapiens | - |
| sciatic nerve | fetal | Homo sapiens | - |
| sciatic nerve | fetal, increased amounts of PAD2 | Homo sapiens | - |
| sciatic nerve | juvenile, increased amounts of PAD2 | Rattus norvegicus | - |
| skin | - |
Rattus norvegicus | - |
| skin | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protein-L-arginine + H2O | - |
Homo sapiens | protein-L-citrulline + NH3 | - |
? | |
| protein-L-arginine + H2O | - |
Rattus norvegicus | protein-L-citrulline + NH3 | - |
? | |
| protein-L-arginine + H2O | citrullination of proteins may exert a specific role in the course of PNS development and repair | Homo sapiens | protein-L-citrulline + NH3 | - |
? | |
| protein-L-arginine + H2O | citrullination of proteins may exert a specific role in the course of PNS development and repair | Rattus norvegicus | protein-L-citrulline + NH3 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PAD | - |
Homo sapiens |
| PAD | - |
Rattus norvegicus |
| peptidylarginine deiminase | - |
Homo sapiens |
| peptidylarginine deiminase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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