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Literature summary for 3.5.3.15 extracted from
- Microglial expression of peptidylarginine deiminase 2 in the prenatal rat brain (2007), Cell. Mol. Biol. Lett., 12, 536-544.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent on | Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | PAD2 is involved in some processes of neurodegeneration and myelination in the central nervous system | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Wistar rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| cerebrum | embryonal, isozyme expression analysis, PAD2 expression occurs also in 19- to 21-day-old embryos at a developmental stage well before myelination begins, overview | Rattus norvegicus | - |
| embryo | - |
Rattus norvegicus | - |
| hippocampus | embryonal, in the prospective dentate gyrus, microglial marker-negative cells show expression of PAD isozyme 2, but not of isozymes PAD1,3, and 4, overview | Rattus norvegicus | - |
| microglia | embryonal, in the prospective medulla | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | PAD2 is involved in some processes of neurodegeneration and myelination in the central nervous system | Rattus norvegicus | ? | - |
? | |
| N-alpha-benzoyl-L-arginine + H2O | - |
Rattus norvegicus | N-alpha-benzoyl-L-citrulline + NH3 | - |
? | |
| N-alpha-benzoyl-L-arginine ethyl ester + H2O | - |
Rattus norvegicus | N-alpha-benzoyl-L-citrulline ethyl ester + NH3 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PAD type 2 | - |
Rattus norvegicus |
| PAD2 | - |
Rattus norvegicus |
| peptidylarginine deiminase 2 | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Rattus norvegicus |
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Release 2023.1 (January 2023)
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