Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9ULC6 | - |
- |
Homo sapiens | Q9ULW8 | - |
- |
Homo sapiens | Q9Y2J8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epidermis | expression of isoform PAD3 is restricted to granular layer and lower stratum corneum | Homo sapiens | - |
epidermis | isoform PAD1 is detected in all layers of the epidermis, including the stratum corneum | Homo sapiens | - |
keratinocyte | expression of isoform PAD2 in all layers of living keratinocytes with a gradient of expression increasing from the basal (very low detection) to the granular layer, where the protein is located at the cell periphery | Homo sapiens | - |
stratum corneum | isoform PAD1 | Homo sapiens | - |
stratum corneum | isoform PAD3 is expressed in granular level of stratum corneum | Homo sapiens | - |
stratum granulosum | expression of isoform PAD2 | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
filaggrin L-arginine + H2O | isoform PAD1 | Homo sapiens | filaggrin L-citrulline + NH3 | - |
? | |
filaggrin L-arginine + H2O | isoform PAD3 | Homo sapiens | filaggrin L-citrulline + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAD1 | - |
Homo sapiens |
PAD2 | - |
Homo sapiens |
PAD3 | - |
Homo sapiens |