Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli strain DH5alpha | Schistosoma mansoni |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-cysteine | strongly blocked SmARG-activity | Schistosoma mansoni | |
L-histidine | strongly blocked SmARG-activity | Schistosoma mansoni | |
L-ornithine | moderately inhibitory | Schistosoma mansoni | |
additional information | L-lysine and diaminopimelic acid failed to block SmARG activity | Schistosoma mansoni | |
NOHA | - |
Schistosoma mansoni | |
Nomega-hydroxy-nor-L-arginine | norNOHA | Schistosoma mansoni |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
17 | - |
L-arginine | pH 10, 37°C | Schistosoma mansoni |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | - |
Schistosoma mansoni |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
6 * 40000, SDS-PAGE | Schistosoma mansoni |
240000 | - |
gel filtration | Schistosoma mansoni |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Schistosoma mansoni | infection of mice with Schistosoma mansoni cercariae elevates arginase activity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schistosoma mansoni | Q6TA39 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Schistosoma mansoni |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
669 | - |
- |
Schistosoma mansoni |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + H2O | - |
Schistosoma mansoni | L-ornithine + urea | - |
? | |
additional information | infection of mice with Schistosoma mansoni cercariae elevates arginase activity | Schistosoma mansoni | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
hexamer | 6 * 40000, SDS-PAGE | Schistosoma mansoni |
Synonyms | Comment | Organism |
---|---|---|
arginase | - |
Schistosoma mansoni |
SmARG | - |
Schistosoma mansoni |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Schistosoma mansoni |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
537 | - |
L-arginine | pH 10, 37°C | Schistosoma mansoni |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
10 | - |
assay at | Schistosoma mansoni |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
1.9 | - |
L-ornithine | pH 10, 37°C | Schistosoma mansoni |