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Literature summary for 3.5.3.1 extracted from

  • Yang, L.; Lewis, C.M.; Chandrasekharan, U.M.; Kinney, C.M.; Dicorleto, P.E.; Kashyap, V.S.
    Arginase activity is increased by thrombin: a mechanism for endothelial dysfunction in arterial thrombosis (2006), J. Am. Coll. Surg., 203, 817-826.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information fibrin has no effect on arginase activity Homo sapiens
thrombin endothelial cell exposition to 10 U/ml thrombin for 4 h leads to 1.6fold increased arginase activity Homo sapiens
thrombin receptor antagonist peptide endothelial cell exposition to 10 U/ml thrombin receptor antagonist peptide for 4 h leads to increased arginase activity Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginine + H2O Homo sapiens
-
L-ornithine + urea
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HUVEC cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O
-
Homo sapiens L-ornithine + urea
-
?