Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Shewanella algae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
Imipenem | 30°C, pH 7.0 | Shewanella algae | |
0.02 | - |
ticarcillin | 30°C, pH 7.0 | Shewanella algae | |
0.025 | - |
benzylpenicillin | 30°C, pH 7.0 | Shewanella algae | |
0.07 | - |
cephalothin | 30°C, pH 7.0 | Shewanella algae | |
0.11 | - |
piperacillin | 30°C, pH 7.0 | Shewanella algae | |
0.19 | - |
Cloxacillin | 30°C, pH 7.0 | Shewanella algae | |
0.39 | - |
Oxacillin | 30°C, pH 7.0 | Shewanella algae | |
0.5 | - |
ampicillin | 30°C, pH 7.0 | Shewanella algae | |
0.5 | - |
meropenem | 30°C, pH 7.0 | Shewanella algae | |
0.67 | - |
cefpirome | 30°C, pH 7.0 | Shewanella algae | |
0.75 | - |
cephaloridine | 30°C, pH 7.0 | Shewanella algae | |
4.7 | - |
ceftazidime | 30°C, pH 7.0 | Shewanella algae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Shewanella algae | Q6VCW0 | clinical isolate KB-1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ampicillin + H2O | - |
Shewanella algae | (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? | |
benzylpenicillin + H2O | - |
Shewanella algae | (2R,4S)-2-[(R)-carboxy(2-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? | |
cefpirome + H2O | - |
Shewanella algae | (2S)-2-[(R)-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}(carboxy)methyl]-5-[(6,7-dihydro-5H-cyclopenta[b]pyridin-1-ium-1-yl)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylate | - |
? | |
ceftazidime + H2O | - |
Shewanella algae | (2R)-2-[(R)-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}(carboxy)methyl]-5-[(pyridin-1-ium-1-yl)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylate | - |
? | |
cephaloridine + H2O | - |
Shewanella algae | (2R)-2-[(R)-carboxy[(thiophen-2-ylacetyl)amino]methyl]-5-(pyridinium-1-ylmethyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylate | - |
? | |
cephalothin + H2O | - |
Shewanella algae | (2R)-5-[(acetyloxy)methyl]-2-[(R)-carboxy[(thiophen-2-ylacetyl)amino]methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? | |
cloxacillin + H2O | - |
Shewanella algae | (2R,4S)-2-[(R)-carboxy{[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? | |
imipenem + H2O | - |
Shewanella algae | (5R)-5-[(1S,2R)-1-carboxy-2-hydroxypropyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid | - |
? | |
meropenem + H2O | - |
Shewanella algae | (4R,5S)-5-[(1S,2R)-1-carboxy-2-hydroxypropyl]-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid | - |
? | |
oxacillin + H2O | - |
Shewanella algae | (2R,4S)-2-{(R)-carboxy[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]methyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? | |
piperacillin + H2O | - |
Shewanella algae | (2R,4S)-2-[(R)-carboxy[[(2R)-2-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]-2-phenylacetyl]amino]methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? | |
ticarcillin + H2O | - |
Shewanella algae | (2R,4S)-2-[(R)-carboxy[[(2R)-2-carboxy-2-(thiophen-3-yl)acetyl]amino]methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carbapenem-hydrolyzing ambler class D beta-lactamase | - |
Shewanella algae |
OXA-55 | - |
Shewanella algae |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
meropenem | 30°C, pH 7.0 | Shewanella algae | |
0.1 | - |
Imipenem | 30°C, pH 7.0 | Shewanella algae | |
0.1 | - |
cefpirome | 30°C, pH 7.0 | Shewanella algae | |
0.5 | - |
Cloxacillin | 30°C, pH 7.0 | Shewanella algae | |
0.6 | - |
cephalothin | 30°C, pH 7.0 | Shewanella algae | |
1 | - |
ticarcillin | 30°C, pH 7.0 | Shewanella algae | |
2 | - |
ceftazidime | 30°C, pH 7.0 | Shewanella algae | |
3 | - |
piperacillin | 30°C, pH 7.0 | Shewanella algae | |
4 | - |
benzylpenicillin | 30°C, pH 7.0 | Shewanella algae | |
5 | - |
Oxacillin | 30°C, pH 7.0 | Shewanella algae | |
8 | - |
ampicillin | 30°C, pH 7.0 | Shewanella algae | |
10 | - |
cephaloridine | 30°C, pH 7.0 | Shewanella algae |