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Literature summary for 3.5.2.3 extracted from
- Interconvension of carbamyl-L-aspartate and L-dihydroorotate by dihydroorotase from mouse Ehrlich ascites carcinoma (1979), J. Biol. Chem., 254, 12506-12512.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.04 | - |
L-carbamoylaspartate | - |
Mus musculus |  |
| 0.12 | - |
L-dihydroorotate | - |
Mus musculus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-carbamoyl-L-aspartate | Mus musculus | - |
L-dihydroorotate + H2O | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial purification | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-carbamoylaspartate | - |
Mus musculus | L-dihydroorotate + H2O | - |
r | |
| N-carbamoyl-L-aspartate | - |
Mus musculus | L-dihydroorotate + H2O | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| multimer | - |
Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.4 | - |
cyclisation of L-carbamoylaspartate | Mus musculus |
| 8.4 | - |
hydrolysis of L-dihydroorotate | Mus musculus |
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