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Literature summary for 3.5.2.3 extracted from

  • Bidigare, R.R.; Sander, E.G.; Pettigrew, D.W.
    Evidence for a pH-dependent isomerization of Clostridium oroticum dihydroorotase (1985), Biochim. Biophys. Acta, 831, 159-160.
    View publication on PubMed
Search for more literature for 3.5.2.3

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Faecalicatena orotica
N-formylaspartate competitive inhibitor Faecalicatena orotica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.015
-
 L-carbamoylaspartate
-
 Faecalicatena orotica
0.028
-
 L-dihydroorotate
-
 Faecalicatena orotica

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
 Faecalicatena orotica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-carbamoyl-L-aspartate Faecalicatena orotica
-
 L-dihydroorotate + H2O
-
 r

Organism

Organism UniProt Comment Textmining
Faecalicatena orotica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-carbamoylaspartate
-
 Faecalicatena orotica L-dihydroorotate + H2O
-
 r
N-carbamoyl-L-aspartate
-
 Faecalicatena orotica L-dihydroorotate + H2O
-
 r

Subunits

Subunits Comment Organism
dimer
-
 Faecalicatena orotica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
 cyclisation of L-carbamoylaspartate Faecalicatena orotica
8
-
 hydrolysis of L-dihydroorotate Faecalicatena orotica