Literature summary for 3.5.1.98 extracted from

Jung, J.C.; Moon, H.I.; Oh, S.
Synthesis, structural characterization and biological evaluation of N-protected cyclopropylethylcarbamates as potential histone deacetylase inhibitor (2008), Chem. Biol. Drug Des., 72, 592-595.

Search for more literature for 3.5.1.98

Application

Application	Comment	Organism
medicine	HDAC inhibitors have attracted a great deal of interest as drug targets	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
(3S)-3-{[(3S)-3-{[(benzyloxy)carbonyl]amino}-3-cyclopropylpropanoyl]amino}-2-oxo-5-phenylpentyl acetate	-	Homo sapiens
apicidin	natural inhibitor	Homo sapiens
FK-228	natural inhibitor	Homo sapiens
suberoylanilide hydroxamic acid	SAHA, synthetic inhibitor	Homo sapiens
trapoxin B	natural inhibitor	Homo sapiens
trichostatin A	natural inhibitor	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
using a mono Q HR5-5 column	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
K-562 cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
HDAC	-	Homo sapiens
histone deacetylase	-	Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	activity assay	Homo sapiens

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Release 2023.1 (January 2023)